Androgenic alopecia (AGA), mafi yawan nau'in asarar gashi, cuta ce ta ci gaba da asarar gashi wanda ke farawa tun lokacin samartaka ko kuma ƙarshen samartaka.Yawan maza a cikin ƙasata ya kai kusan kashi 21.3%, kuma yawan mata ya kai kusan 6.0%.Ko da yake wasu malaman sun ba da shawarar ka'idoji don ganowa da kuma kula da alopecia na androgenetic a kasar Sin a baya, sun fi mayar da hankali kan ganewar asali da magani na AGA, kuma sauran zaɓuɓɓukan magani ba su da yawa.A cikin 'yan shekarun nan, tare da girmamawa a kan maganin AGA, wasu sababbin zaɓuɓɓukan magani sun fito.
Etiology da Pathogenesis
AGA wata cuta ce da ke tattare da kwayar halitta.Binciken cututtukan cikin gida ya nuna cewa 53.3% -63.9% na marasa lafiya na AGA suna da tarihin iyali, kuma layin uba yana da girma fiye da layin mahaifa.Binciken da aka yi a halin yanzu gaba ɗaya-genome da nazarin taswira sun gano ƙwayoyin cuta da yawa, amma har yanzu ba a gano kwayoyin halittarsu ba.Binciken na yanzu ya nuna cewa androgens suna taka muhimmiyar rawa a cikin pathogenesis na AGA;wasu dalilai ciki har da kumburi a kusa da gashin gashi, ƙara yawan matsa lamba na rayuwa, tashin hankali da damuwa, da rashin talauci da halin cin abinci na iya kara tsananta alamun AGA.Androgens a cikin maza galibi suna fitowa ne daga testosterone wanda ƙwai suka ɓoye;androgens a cikin mata galibi suna fitowa ne daga hadadden cortex na adrenal da kuma karamin adadin sinadari daga ovaries, androgen shine yafi androstenediol, wanda za'a iya daidaita shi zuwa testosterone da dihydrotestosterone.Ko da yake androgens sune mahimmancin mahimmanci a cikin pathogenesis na AGA, matakan da ke gudana a cikin kusan dukkanin marasa lafiya na AGA ana kiyaye su a matakan al'ada.Nazarin ya nuna cewa tasirin androgens akan gashin gashi mai saukin kamuwa ya karu saboda karuwar kwayar halittar mai karɓar isrogen da / ko ƙara yawan nau'in nau'in II 5α reductase gene a cikin gashin gashi a cikin yankin alopecia.Don AGA, ƙwayoyin ɓangarorin dermal na ƙwayar gashi mai sauƙi sun ƙunshi takamaiman nau'in II 5a reductase, wanda zai iya juyar da testosterone na androgen da ke yaduwa zuwa yanki a cikin jini zuwa dihydrotestosterone ta hanyar ɗaure zuwa mai karɓa na intracellular androgen.Ƙaddamar da jerin halayen da ke haifar da ci gaba da rage yawan gashi da asarar gashi zuwa gashi.
Bayyanar Clinical da Shawarwari na Jiyya
AGA wani nau'i ne na alopecia mara tabo wanda yawanci yakan fara ne a lokacin samartaka kuma yana da alaƙa da ci gaba da ɓarkewar diamita na gashi, asarar gashi, da alopecia har zuwa nau'i daban-daban na gashin gashi, yawanci yana tare da alamun ƙarar gashin kai.
Aikace-aikacen PRP
Matsalolin platelet yayi daidai da yawan adadin platelet sau 4-6 a cikin jini gaba ɗaya.Da zarar an kunna PRP, α granules a cikin platelets za su saki babban adadin abubuwan ci gaba, ciki har da nau'in haɓakar haɓakar platelet, canza yanayin girma-β, nau'in haɓakar insulin-kamar girma, haɓakar haɓakar epidermal da haɓakar haɓakar endothelial na jijiyoyin jini, da sauransu. na inganta haɓakar gashin gashi, amma ƙayyadaddun tsarin aikin ba cikakke ba ne.Amfani da shi shine a yi amfani da PRP a cikin gida a cikin dermis Layer na fatar kai a cikin alopecia, sau ɗaya a wata, kuma ci gaba da yin allura sau 3 zuwa 6 na iya ganin wani tasiri.Kodayake bincike daban-daban na asibiti a gida da waje sun rigaya sun tabbatar da cewa PRP tana da wani tasiri akan AGA, babu wani daidaitaccen tsari na shirye-shiryen PRP, don haka ƙimar maganin PRP ba daidai ba ne, kuma ana iya amfani da shi azaman taimako. yana nufin don maganin AGA a wannan mataki.
(Ana sake buga abubuwan da ke cikin wannan labarin, kuma ba mu bayar da garantin bayyananne ko bayyananniyar garanti don daidaito, amintacce ko cikar abubuwan da ke cikin wannan labarin ba, kuma ba mu da alhakin ra'ayoyin wannan labarin, da fatan za a fahimta.)
Lokacin aikawa: Agusta-02-2022